Non-maximal entanglement of photons from positron-electron annihilation demonstrated using a novel plastic PET scanner
P. Moskal, D. Kumar, S. Sharma, E.Y. Beyene, N. Chug, A. Coussat, C. Curceanu, E. Czerwinski, M. Das, K. Dulski, M. Gorgol, B. Jasinska, K. Kacprzak, T. Kaplanoglu, L. Kaplon, K. Klimaszewski, T. Kozik, E. Lisowski, F. Lisowski, W. Mryka, S. Niedzwiecki, S. Parzych, E.P. del Rio, L. Raczynski, M. Radler, R.Y. Shopa, M. Skurzok, E. L. Stepien, P. Tanty, K. Tayefi Ardebili, K. Valsan Eliyan, W. Wislicki
abstract
In the state-of-the-art Positron Emission Tomography (PET), information about the polarization of annihilation photons is not available. Current PET systems track molecules labeled with positron-emitting radioisotopes by detecting the propagation direction of two photons from positron-electron annihilation. However, annihilation photons carry more information than just the site where they originated. Here we present a novel J-PET scanner built from plastic scintillators, in which annihilation photons interact predominantly via the Compton effect, providing information about photon polarization in addition to information on photon direction of propagation. Theoretically, photons from the decay of positronium in a vacuum are maximally entangled in polarization. However, in matter, when the positron from positronium annihilates with the electron bound to the atom, the question arises whether the photons from such annihilation are maximally entangled. In this work, we determine the distribution of the relative angle between polarization orientations of two photons from positron-electron annihilation in a porous polymer. Contrary to prior results for positron annihilation in aluminum and copper, where the strength of observed correlations is as expected for maximally entangled photons, our results show a significant deviation. We demonstrate that in porous polymer, photon polarization correlation is weaker than for maximally entangled photons but stronger than for separable photons. The data indicate that more than 40% of annihilations in Amberlite resin lead to a non-maximally entangled state. Our result indicates the degree of correlation depends on the annihilation mechanism and the molecular arrangement. We anticipate that the introduced Compton interaction-based PET system opens a promising perspective for exploring polarization correlations in PET as a novel diagnostic indicator.
Feasibility studies for imaging e+e- annihilation with modular multi-strip detectors
S. Sharma, L. Povolo, S. Mariazzi, G. Korcyl, K. Kacprzak, D. Kumar, S. Niedzwiecki, J. Baran, E. Beyene, R. S. Brusa, R. Caravita, N. Chug, A. Coussat, C. Curceanu, E. Czerwinski, M. Dadgar, M. Das, K. Dulski, K. Eliyan, A. Gajos, N. Gupta, B. C. Hiesmayr, L. Kaplon, T. Kaplanoglu, K. Klimaszewski, P. Konieczka, T. Kozik, M. K. Kozani, W. Krzemien, S. Moyo, W. Mryka, L. Penasa, S. Parzych, E. Perez Del Rio, L. Raczynski, R. Y. Shopa, M. Skurzok, E. L. Stepien, P. Tanty, F. Tayefi, K. Tayefi, W. Wislicki, P. Moskal
abstract
Studies based on imaging the annihilation of the electron (e-) and its antiparticle positron (e+) open up several interesting applications in nuclear medicine and fundamental research. The annihilation process involves both the direct conversion of ee into photons and the formation of their atomically bound state, the positronium atom (Ps), which can be used as a probe for fundamental studies. With the ability to produce large quantities of Ps, manipulate them in long-lived Ps states, and image their annihilations after a free fall or after passing through atomic interferometers, this purely leptonic antimatter system can be used to perform inertial sensing studies in view of a direct test of Einstein equivalence principle. It is envisioned that modular multistrip detectors can be exploited as potential detection units for this kind of studies. In this work, we report the results of the first feasibility study performed on a e beamline using two detection modules to evaluate their reconstruction performance and spatial resolution for imaging ee annihilations and thus their applicability for gravitational studies of Ps.
Discrete symmetries tested at 10^-4 precision using linear polarization of photons from positronium annihilations
P. Moskal, E. Czerwiński, J. Raj, S. D. Bass, E. Beyene, N. Chug, A. Coussat, C. Curceanu, M. Dadgar, M. Das, K. Dulski, A. Gajos, M. Gorgol, B. C. Hiesmayr, B. Jasińska, K. Kacprzak, T. Kaplanoglu, Ł. Kapłon, K. Klimaszewski, P. Konieczka, G. Korcyl, T. Kozik, W. Krzemień, D. Kumar, S. Moyo, W. Mryka, S. Niedźwiecki, S. Parzych, E. Pérez del Río, L. Raczyński, S. Sharma, S. Choudhary, R. Y. Shopa, M. Silarski, M. Skurzok, E. Ł. Stępień, P. Tanty, F. T. Ardebili, K. T. Ardebili, K. V. Eliyan, W. Wiślicki
abstract
Discrete symmetries play an important role in particle physics with violation of CP connected to the matter-antimatter imbalance in the Universe. We report the most precise test of P, T and CP invariance in decays of ortho-positronium, performed with methodology involving polarization of photons from these decays. Positronium, the simplest bound state of an electron and positron, is of recent interest with discrepancies reported between measured hyperfine energy structure and theory at the level of 10^-4 signaling a need for better understanding of the positronium system at this level. We test discrete symmetries using photon polarizations determined via Compton scattering in the dedicated J-PET tomograph on an event-by-event basis and without the need to control the spin of the positronium with an external magnetic field, in contrast to previous experiments. Our result is consistent with QED expectations at the level of 0.0007 and one standard deviation.
Estimating influence of positron range in proton-therapy-beam monitoring with PET
W. Mryka, M. Das, E.Y. Beyene, P. Moskal, E. Stępień
abstract
The application of PET scanners to proton-beam-therapy monitoring is a promising solution to obtain the range of the beam and hence the positions of a Bragg peak - maximum dose deposition point. A proton beam induces nuclear reactions in the tissue, leading to the production of isotopes that emit beta+ radiation. This enables the imaging of the density distribution of beta+ isotopes produced in the body, allowing the reconstruction of the proton beam range. Moreover, PET detectors may open the possibility for in-beam monitoring, which would offer an opportunity to verify the range during irradiation. PET detectors may also allow positronium imaging, which would be the indicator of the tissue conditions. However, the image of annihilation points does not represent the range of the proton beam. There are several factors influencing the translation from annihilation points to obtain the Bragg peak position. One of them is the kinetic energy of the positron. This energy corresponds to some range of the positron within the tissue. In this manuscript we estimate positron energy and its range and discuss its influence on proton therapy monitoring.
Exploration of simultaneous dual-isotope imaging with multi-photon modular J-PET scanner
Ermias Yitayew Beyene, Manish Das, Martyna Durak-Kozica, Grzegorz Korcyl, Wiktor Mryka, Szymon Niedźwiecki, Szymon Parzych, Keyvan Tayefi Ardebili, Rafał Walczak, Kamil Wawrowicz, Ewa Stępień, Paweł Moskal
abstract
The modular J-PET scanner, comprising 24 compact and versatile modules, each consisting of 13 plastic strips with four SiPM detectors at the ends, represents a powerful tool for clinical applications in nuclear medical imaging. This study presents preliminary results from the exploration of simultaneous dual-isotope imaging using the modular J-PET system. Our approach involved two isotopes: 68Ge, characterized by a ringlike shape, and 22Na, exhibiting a point-like shape. The imaging was based on double-coincidence and triple-coincidence events. In the double coincidence case, both isotopes contributed comparably, whereas in the triple coincidence case 22Na dominated due to the prompt gamma being emitted with 100% of positron emissions, unlike 68Ga, where the prompt gamma was emitted in only 1.3% of cases after positron emission. In this work we present direct 2? images determined for two-signal events and images for three-signal events, with two signals from annihilation photons and one from a prompt gamma. These results showcase the preliminary findings from simultaneous dual-isotope imaging of 68Ga and 22Na isotopes using the modular J-PET scanner, which will be presented and discussed.
Estimating the efficiency and purity for detecting annihilation and prompt photons for positronium imaging with J-PET using toy Monte Carlo simulation
M. Das, W. Mryka, E.Y. Beyene, S. Parzych, S. Sharma, E. Stępień, P. Moskal
abstract
The positronium imaging technique represents a potential enhancement of the PET imaging method. Its core principle involves employing a beta+ radiation source that emits additional gamma quanta referred to as prompt gamma. Our aim is to evaluate the capability to differentiate between annihilation and prompt gamma emissions, a vital aspect of positronium imaging. For this purpose, the selected isotopes should enable high efficiency and purity in detecting both prompt gamma and annihilation gamma. The assessment of the efficiency in identifying prompt and annihilation photons for various isotopes, which are potentially superior candidates for beta++ gamma emitters, is conducted through toy Monte-Carlo simulation utilizing the cross-section formula for photon-electron scattering. In this article, we have performed calculations for efficiency and purity values across different isotopes under ideal conditions and examined how these values evolve as we incorporate the fractional energy resolution into the analysis. Ultimately, the primary goal is to determine the energy threshold that optimizes both efficiency and purity, striking a balance between accurately identifying and recording events of interest while minimizing contamination from undesired events.
Performance of NEMA characteristics of Modular J-PET
F. Tayefi Ardebili, S. Niedźwiecki, J. Baran, E. Beyene, D. Borys, K. Brzezinski, N. Chug, A. Coussat, C. Curceanu, E. Czerwiński, M. Dadgar, K. Dulski, K. Eliyan, J. Gajewski, A. Gajos, B. Hiesmayr, A. Jędruszczak, K. Kacprzak, M. Kajetanowicz, T. Kaplanoglu, Ł. Kapłon, K. Klimaszewski, G. Korcyl, T. Kozik, W. Krzemień, D. Kumar, G. Łapkiewicz, W. Migdał, S. Moyo, W. Mryka, S. Parzych, E. Pérez del Río, L. Raczyński, S. Sharma, S. Shivani, R. Shopa, M. Skurzok, P. Tanty, K. Tayefi Ardebili, W. Wislicki, E. Stępień, P. Moskal
published in: 2023 IEEE Nuclear Science Symposium, Medical Imaging Conference and International Symposium on Room-Temperature Semiconductor Detectors
The Modular J-PET scanner, developed by the J-PET collaboration, is a new prototype PET scanner developed based on axially arranged plastic scintillators as a large axial field of view (50cm) affordable tomograph. In this study, the performance characteristics of the scanner were evaluated according to NEMA NU2-2018 standards using Monte Carlo simulation. In order to ensure the selection of true coincidence events, certain criteria were established. Specifically, each photon emitting from a single annihilation must deposit at least 200 keV within 4 ns of a coincidence time window. The preliminary results showed that the sensitivity profile peak was 4 cps/kBq at the center of the detector, While the scatter fraction was estimated to be 39% using the single slice rebinning algorithm. Spatial resolution was estimated around 4.5 mm in the radial and tangential direction and 18 mm in the axial direction.
Estimating the efficiency and purity for detecting annihilation and prompt photons with J-PET using toy Monte Carlo simulation
Manish Das, Wiktor Mryka, Ermias Y. Beyene, Szymon Parzych, Pawel Moskal
Symposium on new trends in nuclear and medical physics, October 18-20, 2023
